
When it comes to exercise, we've all had our fair share of moments when the couch seems more appealing than the treadmill. It's easy to chalk it up to a case of "I'll start tomorrow" or "I'm just naturally inclined to be a couch potato." But what if there's more to the story? What if the seemingly inexplicable allure of inactivity isn't just a product of laziness but rather a result of complex neural dynamics? Enter Brain-Derived Neurotrophic Factor (BDNF), the unsung hero of exercise motivation. In this article, we'll uncover the intriguing connection between your brain, BDNF, and the willpower (or lack thereof) that keeps you on the couch or propels you to lace up those running shoes. Strap in; it's time to give your brain some credit.
What is the BDNF gene and what are its functions?
Brain-Derived Neurotrophic Factor (BDNF) is a protein encoded by the BDNF gene in humans. It is critical for the growth, survival, and function of neurons in the nervous system. It plays a vital role in learning, memory, neuroplasticity, mood regulation, and overall brain health. Disruptions in BDNF function have been linked to various neurological and psychiatric disorders, highlighting its importance in maintaining optimal brain function.
What role does the BDNF gene play in motivation to exercise?
The BDNF (Brain-Derived Neurotrophic Factor) gene is thought to play a significant role in motivation to exercise through its influence on various aspects of brain function and neuroplasticity. Here's how BDNF is associated with motivation to exercise:
1. Neuroplasticity and Learning: BDNF is involved in neuroplasticity, which is the brain's ability to reorganize and adapt in response to experiences and learning. When you exercise, especially during aerobic activities like running or swimming, your brain releases BDNF. This release is believed to facilitate the formation of new neural connections and enhance synaptic plasticity. This can improve your ability to learn and adapt to new activities, including exercise routines.
2. Mood Regulation: BDNF is associated with mood regulation and can have antidepressant effects. Exercise itself is known to improve mood by increasing the release of neurotransmitters like serotonin and endorphins. BDNF may play a role in this process by supporting the growth and maintenance of neurons in brain regions related to mood regulation. When you feel better after exercising, you may be more motivated to continue doing it.
3. Stress Resilience: Regular exercise can increase your resilience to stress, and BDNF appears to be involved in this process. Exercise-induced BDNF release may help protect against the negative effects of stress on the brain. When you experience less stress and anxiety, you may find it easier to stay motivated to exercise.
4. Long-Term Commitment: BDNF's role in neuroplasticity can support the formation of long-term habits. When you engage in exercise regularly and consistently, it can lead to changes in the brain that make exercise feel more rewarding and less effortful over time. This can reinforce your motivation to continue exercising.
5. Cognitive Function: BDNF is linked to cognitive function, including memory and executive function. Regular exercise has been shown to improve cognitive function, and BDNF may contribute to these improvements. Enhanced cognitive function can lead to better planning and goal-setting, which are crucial for maintaining an exercise routine.
6. Energy and Endurance: BDNF may indirectly influence motivation by enhancing energy levels and physical endurance. When exercise becomes less physically taxing due to improved fitness, individuals may be more motivated to engage in physical activities.
It's important to note that genetics can influence individual variations in BDNF levels and responsiveness to exercise. Some people may naturally have higher BDNF levels, which could make them more predisposed to find exercise motivating and enjoyable. If you’d like to see if your levels are high, check out our genetic tests here (both the Health and Sports Genetic Tests include results for BDNF).
While BDNF is a key player in the motivation to exercise, it's just one piece of the puzzle. Other factors, such as personal goals, social support, environmental cues, and individual preferences, also play roles in motivating and sustaining an exercise routine.
What can be done to increase BDNF to improve motivation to exercise?
Enhancing Brain-Derived Neurotrophic Factor (BDNF) activity can be a valuable strategy to boost exercise motivation and improve overall brain health. Here are several approaches that may help increase BDNF activity:
1. Regular Exercise: The most effective way to increase BDNF levels is through physical activity. Engaging in regular aerobic exercises like running, swimming, or brisk walking has been shown to significantly elevate BDNF levels. Aim for at least 150 minutes of moderate-intensity aerobic exercise per week.
2. High-Intensity Interval Training (HIIT): HIIT workouts involve short bursts of intense exercise followed by brief rest periods. HIIT has been found to be particularly effective in raising BDNF levels, potentially more so than steady-state aerobic exercises.
3. Resistance Training: While aerobic exercise is known to increase BDNF, resistance or strength training may also have a positive impact. Combining both aerobic and resistance exercises in your fitness routine can be beneficial.
4. Mind-Body Practices: Activities like yoga and meditation have been associated with increased BDNF levels. These practices can help reduce stress, improve mood, and indirectly enhance exercise motivation.
5. Dietary Choices: Certain foods and dietary patterns can support BDNF production. Include foods rich in antioxidants, omega-3 fatty acids, and polyphenols in your diet. These can be found in fruits, vegetables, fish, nuts, and olive oil. Additionally, a low-carb or ketogenic diet may have a positive impact on BDNF levels.
6. Adequate Sleep: Quality sleep is essential for BDNF production and overall brain health. Aim for 7-9 hours of restful sleep per night to optimize BDNF activity.
7. Stress Reduction: Chronic stress can reduce BDNF levels. Implement stress-reduction techniques like mindfulness, deep breathing exercises, or progressive muscle relaxation to manage stress and anxiety effectively.
8. Intermittent Fasting: Some studies suggest that intermittent fasting can enhance BDNF levels. This dietary approach involves cycling between periods of eating and fasting. Consult a healthcare professional before attempting any fasting regimen.
9. Social Interaction: Engaging in social activities and maintaining strong social connections can support mental well-being and potentially enhance BDNF activity.
10. Cognitive Challenges: Engage in mentally stimulating activities such as puzzles, learning a new skill, or playing musical instruments. These activities can help boost BDNF production in the brain.
11. Supplements: Some supplements, such as curcumin, resveratrol, and fish oil, have shown promise in increasing BDNF levels. However, it's essential to consult a healthcare provider before adding any supplements to your regimen.
12. Mediation and Relaxation: Practices like meditation, progressive muscle relaxation, and mindfulness can help reduce stress and promote a positive mood, indirectly supporting BDNF activity.
It's important to note that individual responses to these strategies can vary, and there is no one-size-fits-all approach. A combination of these approaches, tailored to your preferences and needs, may be the most effective way to enhance BDNF activity and, in turn, boost exercise motivation and overall brain health. Before making significant lifestyle changes, it's advisable to consult with a healthcare professional for personalized guidance.
In Summary
In the quest for exercise motivation, it's easy to label our reluctance as mere laziness. But as we've uncovered the fascinating world of Brain-Derived Neurotrophic Factor (BDNF), we've learned that there's more to the story than meets the eye. Your brain, armed with BDNF, holds a significant role in shaping your workout decisions. This unsung hero influences your ability to stay on the couch or lace up those running shoes. So, as we wrap up this exploration of the intricate connection between your brain, BDNF, and exercise motivation, remember that it's not just about laziness. By adopting a holistic approach that includes regular exercise, mindful dietary choices, stress management, and cognitive challenges, you can harness the power of BDNF to boost your motivation and embark on a healthier, more active lifestyle. Give your brain the credit it deserves, and you'll find yourself hitting those fitness goals with newfound determination and enthusiasm.
References
Cotman, C. W., & Berchtold, N. C. (2002). Exercise: a behavioral intervention to enhance brain health and plasticity. Trends in Neurosciences, 25(6), 295-301.
Dinoff, A., Herrmann, N., Swardfager, W., Liu, C. S., Sherman, C., Chan, S., ... & Lanctôt, K. L. (2017). The effect of exercise training on resting concentrations of peripheral brain-derived neurotrophic factor (BDNF): a meta-analysis. PLoS ONE, 12(6), e0173810.
Erickson, K. I., Voss, M. W., Prakash, R. S., Basak, C., Szabo, A., Chaddock, L., ... & Kramer, A. F. (2011). Exercise training increases size of hippocampus and improves memory. Proceedings of the National Academy of Sciences, 108(7), 3017-3022.
Griffin, É. W., Mullally, S., Foley, C., Warmington, S. A., O'Mara, S. M., & Kelly, Á. M. (2011). Aerobic exercise improves hippocampal function and increases BDNF in the serum of young adult males. Physiology & Behavior, 104(5), 934-941.
Hötting, K., & Röder, B. (2013). Beneficial effects of physical exercise on neuroplasticity and cognition. Neuroscience & Biobehavioral Reviews, 37(9), 2243-2257.
Rasmussen, P., Brassard, P., Adser, H., Pedersen, M. V., Leick, L., Hart, E., ... & Pilegaard, H. (2009). Evidence for a release of brain-derived neurotrophic factor from the brain during exercise. Experimental Physiology, 94(10), 1062-1069.
Rethorst, C. D., Wipfli, B. M., & Landers, D. M. (2009). The antidepressive effects of exercise: a meta-analysis of randomized trials. Sports Medicine, 39(6), 491-511.
Szuhany, K. L., Bugatti, M., & Otto, M. W. (2015). A meta-analytic review of the effects of exercise on brain-derived neurotrophic factor. Journal of Psychiatric Research, 60, 56-64.
Vaynman, S., & Gomez‐Pinilla, F. (2005). License to run: exercise impacts functional plasticity in the intact and injured central nervous system by using neurotrophins. Neurorehabilitation and Neural Repair, 19(4), 283-295.
Zoladz, J. A., Pilc, A., & Majerczak, J. (2008). Endurance training increases plasma brain-derived neurotrophic factor concentration in young healthy men. Journal of Physiology and Pharmacology, 59(Suppl 7), 119-132.

